Radiotherapy Treatment - MRI Scan

What’s Next For Gamma Knife Radiosurgery & AI Technology?

One of the most effective and advanced treatment resources for brain tumours and vascular malformations is Gamma Knife radiosurgery, which first came to the fore during the 1960s and which has continued to evolve quickly ever since.

With the advent of artificial intelligence (AI) over the last year or so, new and exciting opportunities are starting to emerge… some of which have just been published in the spring edition of SCOPE magazine, with contributions from our own clinical team, including Ian Paddick (consultant physicist at Queen Square) and Hannah Bouas (radiosurgery physicist at Thornbury Radiosurgery Centre).

The focus here is on AI-driven auto-contouring for tumour segmentation, achieving greater levels of precision and more consistent patient outcomes in stereotactic radiosurgery.

Read on to find out more about the key conclusions drawn in the Scope piece.

AI-driven auto-contouring for advanced precision

AI-driven auto-contouring for tumour segmentation is a significant breakthrough in Gamma Knife technology, moving away from manual processes that are time consuming and subject to risks posed by human interpretation, particularly in lesions and tumours that don’t have clearly defined boundaries.

Using AI frameworks allow clinicians to segment tumour boundaries with the equivalent accuracy to human annotators, the advantages of which include:

Reduced human error: Consistency is achieved through AI automation, lowering the risk of inaccurate results while reducing variability and oversights significantly.

Enhanced patient outcomes: AI tools ensure greater accuracy of tumour segmentation, resulting in more precise radiation delivery to tumour cells and reducing damage risks to healthy brain tissue, as well as reducing the risks of complications and side-effects.

Efficiency gains: Automation allows for more efficient contour detection in much shorter timescales, thus allowing for faster overall treatment times and reduced waiting lists.

Potential limitations of AI

Although the Scope article does note that AI is an incredibly valuable tool, models for auto-contouring still have some limitations, such as incomplete training data that may not generalise across diverse populations, or imaging noise that results in false positives.

While AI will undoubtedly become more important as a resource in the future, for now clinical oversight and judgement of contouring processes will still be necessary, particularly for more complex cases such as brain metastases.

Amethyst France Partners with CROMG to Improve Cancer Care

Amethyst Radiotherapy France is proud to announce a strategic partnership with the Centre Radiothérapie Oncologie Moyenne Garonne (CROMG), a renowned radiotherapy centre based in Agen. This new collaboration marks a significant step forward in advancing oncology care in the South of France, uniting two organisations committed to delivering exceptional radiotherapy services through innovation, expertise, and compassion.

Founded in 2008, CROMG has long been recognised as a leader in the region, equipped with three state-of-the-art linear accelerators (Linacs) and a highly experienced medical team. Through this partnership, Amethyst aims to reinforce CROMG’s legacy while introducing enhanced clinical pathways, advanced technologies, and broader access to patient-centric treatment closer to home.

“This partnership reflects our shared vision to provide world-class radiotherapy services and ensure patients across the Nouvelle-Aquitaine region have access to the latest in cancer treatment,” said Olivier Cosset, Amethyst France CEO. “We are excited to welcome the CROMG team into the Amethyst family and support the continued growth of their outstanding medical expertise.”

By integrating resources, teams, and know-how, Amethyst and CROMG will work together to maintain the highest standards of care while expanding access and strengthening local oncology networks. The partnership will also foster the development of multidisciplinary approaches, supporting not only radiotherapy but broader oncology collaboration across the region.

This collaboration marks an exciting milestone in Amethyst’s continued expansion in France, reinforcing its mission to make high-quality, innovative radiotherapy accessible to more patients, wherever they are.


About Amethyst Radiotherapy
Amethyst Radiotherapy is one of Europe’s leading private cancer treatment providers, delivering high-precision radiotherapy services through a network of state-of-the-art centres. With a strong presence in France and across Europe, Amethyst is dedicated to innovation, medical excellence, and improving patient outcomes.

About CROMG
The Centre Radiothérapie Oncologie Moyenne Garonne (CROMG) has been at the heart of cancer care in Agen since 2008. Committed to personalised treatment and cutting-edge radiotherapy, the centre is home to an expert medical team, serving patients across the Nouvelle-Aquitaine region with compassion and excellence.

Media Contact:
Sophie Ward
Email Address: [email protected]
Phone Number: +44 208 713 0460
Organisation Website: www.amethysthealthcare.com

Amethyst Radiotherapy France To Appear On Check-Up Santé

Acclaimed French television show Check-Up Santé on BFM TV , which focuses on health information and regularly invites medical experts onto the stage to discuss important topics of the day, has asked Olivier Cosset, CEO of Amethyst Radiothérapie France, to appear as a guest on Saturday, 22nd February and Sunday 23rd February.

Mr Cossett will be on the BFM TV flagship health programme talking in depth about the latest innovations in radiotherapy and the increasingly important role the practice has to play in modern cancer treatment, delivering insights into how it is evolving to make cancer treatment more effective and accessible.

“Radiotherapy is undergoing a true revolution, with advancements that are making treatments more precise, efficient, and accessible to more patients than ever before. At Amethyst Radiothérapie France, we are committed to bringing the latest innovations in radiotherapy to improve patient care and outcomes. I look forward to discussing these exciting developments on Check-Up Santé with Fabien Guez and shedding light on how radiotherapy is shaping the future of cancer treatment.”

– Olivier Cosset, CEO of Amethyst Radiothérapie France

Amethyst Radiothépie is one of the biggest private providers of radiotherapy services in France, providing cutting-edge treatments to enhance the patient journey and improve health outcomes across the board.

The episode is due to air on 22nd February at 14:00 EST and Sunday 23rd February at 15:00 EST on BFM TV. Make sure you tune in to hear a truly fascinating discussion on radiotherapy innovation and what the future of cancer care will look like.

Also featuring on the show will be Professor Jean-Emmanuel Bibault, who will be talking about the long history of cancer (which dates all the way back to prehistoric times), just one of the points raised in his book Cancer Confidential: L’histoire du cancer, des secrets d’hier aux revolutions de demain.

The Die Presse Front Page

Amethyst Radiotherapy Featured By Die Presse

We are pleased to share that Amethyst Radiotherapy Austria has been featured on the front page of Die Presse, one of Austria’s leading broadsheet newspapers. This recognition highlights our Vienna-based centre’s excellence in delivering advanced radiotherapy services.

This feature underscores the dedication and expertise of our team in providing innovative treatments for complex conditions, particularly cancer—one of the world’s leading causes of mortality.

In the article, Centre Director Paul Stuchetz discusses our commitment to helping patients achieve the best possible outcomes through cutting-edge therapies, with integrative cancer treatment at the core of our approach.

Readers will also find insights into radiation therapy as a treatment option, including the benefits of external beam radiation in managing various cancers. The article highlights prostate cancer, an aggressive disease that requires precise and effective intervention.

At our Vienna clinic, Linear Accelerator (Linac) radiotherapy delivers high-energy X-rays and accelerates electrons to precisely conform to tumour shapes and sizes. This advanced approach ensures cancer cells are effectively targeted while preserving healthy tissue.

To find out more about the treatments we provide, get in touch with the Amethyst Radiotherapy team today.

Amethyst Radiotherapy UK Appoints Sasha Burns as New CEO.

Amethyst Group appoints Sasha Burns as CEO of UK Operations

Amethyst Group is pleased to welcome Sasha Burns as the new Chief Executive Officer (CEO) of UK Operations. With a strong background in healthcare leadership, strategic growth, and operational excellence, Sasha will play a key role in advancing Amethyst’s radiotherapy services and expanding access to world-class cancer treatment.

Bringing over 20 years of experience across both the NHS and independent sector, Sasha has a proven track record in transformational healthcare leadership. She previously held senior leadership roles at Alliance Medical, where she served as Chief Commercial and Operations Officer, and Nuffield Health, where she oversaw a network of hospitals and well-being centres. Her expertise spans business transformation, patient care innovation, and operational strategy.

With a background as a radiographer and an MBA from Henley Business School, Sasha combines clinical insight with strategic leadership, making her well-positioned to enhance Amethyst Group’s commitment to pioneering radiotherapy services.

“I am excited to join Amethyst Group and contribute to its mission of delivering innovative, high-quality radiotherapy care. As demand for advanced cancer treatments grows, I look forward to supporting the UK operations in expanding access and driving excellence,” said Sasha Burns.

Amethyst Group continues to strengthen its clinical expertise, patient-focused care, and cutting-edge radiotherapy technology across its European network. Sasha’s appointment reflects our ongoing commitment to innovation, growth, and leadership in oncology care.

CEO_Stephane Carre_Amethyst Healthcare Group

Stéphane Carré, CEO of Amethyst Healthcare, in The CEO Magazine

We are delighted to announce that Stéphane Carré, CEO of Amethyst Healthcare Group, was recently featured in The CEO Magazine. In this exclusive interview, Stéphane shared his vision for advancing cancer care across Europe, highlighting the innovative solutions, strategic partnerships, and patient-first approach that define Amethyst Healthcare’s mission.

 

 

Prioritising Patient-Centred Care

A cancer diagnosis is life-changing, and Amethyst Healthcare aims to provide clarity, compassion, and confidence during this challenging journey. By integrating advanced radiotherapy as the core of our treatment approach, we focus on improving outcomes while minimising side effects.

As Stéphane Carré explained, radiotherapy remains one of the safest and most cost-effective cancer treatments available today. Its precision and adaptability make it suitable for a wide range of patients and conditions, ensuring we deliver care tailored to individual needs.

Building Strong Partnerships for Growth

Collaboration is at the heart of Amethyst Healthcare’s success. By partnering with public healthcare systems, we enhance access to state-of-the-art facilities while supporting existing medical infrastructure. This approach has enabled us to expand our services from Romania to six countries, including the UK, France, Italy, Austria, and Poland. Plans are already underway to enter a seventh European market, furthering our commitment to providing high-quality care.

Innovating for a Better Tomorrow

At Amethyst, we’re constantly looking to the future. From developing mobile apps to provide patients with personalised treatment data to streamlining diagnosis and therapy pathways, innovation drives everything we do. Stéphane Carré emphasised that creating an environment of trust and support for patients and their families is critical to achieving the best outcomes.

A Vision for the Future

Looking ahead, Amethyst Healthcare is focused on both expanding its current facilities and acquiring new ones to broaden its reach. This twofold growth strategy ensures we can serve more patients while continuing to provide timely, accessible, and effective cancer care.

Stéphane Carré summed it up best: “When patients feel supported and cared for, their outcomes improve. That’s the foundation of everything we do at Amethyst Healthcare.”

 

Read the full interview with Stéphane Carré in The CEO Magazine for more insights into Amethyst Healthcare Group’s inspiring journey.
Stéphane Carré, CEO of Amethyst Radiotherapy in HBI Interview

Amethyst CEO Stéphane Carré Discusses Growth and Patient-Centric Care in Recent HBI Interview

In this interview of pan-European radiotherapy provider Amethyst Radiotherapy, explains how his company is aiming to increase access to state of the art radiotherapy services, and provide a holistic care journey geared towards making the patient feel as comfortable as possible. Stéphane Carré will be sharing more about his business model at HBI 2025, in Paris, March 24-26, 2025. Click here to find out more.


Expanding Access and Patient Comfort in Radiotherapy

Amethyst is a private provider of cancer care, specialising in radiotherapy treatment. It was founded 15 years ago in Romania but has since expanded to 16 centres across six European countries. It has seven centres in France, four in Romania, two in the UK, one in Austria, one in Italy, and one in Poland.

The company treats more than 40,000 patients across Europe each year, more than any other private cancer care provider.

“We’re growing very fast and will soon announce the opening of a few more centres,” Carré says.

“From day one, our model has been to provide radiotherapy in areas which are not well covered. Some countries still have ‘white zones’ where radiotherapy is not available, and patients must travel long distances to reach medical centres where they can receive it. Living in the countryside should not be a reason for not being able to access treatment. Through expanding our footprint, we’re reaching more and more patients who couldn’t access proper treatments previously. When we’re able to develop in those zones it gives us a lot of satisfaction.”


Advancing Technology and Personalised Patient Care

“Our other key ambition is to make sure we’re at the forefront of what’s available in terms of clinical quality and efficiency and provide the best possible technology and know-how to patients. We provide quite a high-tech environment, and we’re moving towards more adaptive, personalised treatments. That’s really our goal.”

Carré adds that a third key element to the group’s business model is its ambition to make the patient feel as comfortable and at-ease as possible in their treatment journey.

“We provide both pre and post treatment services to the patient, designed to give them peace of mind. We provide services such as counselling, dieticians, or any other kind of medical service that comes after radiotherapy to help them recover fully,” Carré explains.

“This is a personal conviction that I’ve developed across my career in healthcare: whatever kind of treatment you’re providing — curative, palliative, or preventive — it’s critical to provide the patient not only with the best solution but to do so within a caring and comfortable environment. This is something I really want to focus on across all Amethyst centres.”

Part of the motivation for this holistic approach is the increasing survival rates for cancer over the past couple of decades. “An increasing number of patients who are living with cancer are coming back for recurrent treatments.”


Digital Innovation and Expansion Beyond Radiotherapy

Digitalisation of access to care is one way that Amethyst aims at to make patients’ journeys smoother:

“We have different levels of digital deployment in different countries. But we have various digital tools to take care of patients from the moment they enter the centre; AI and digital tools are heavily present. Our goal is to have a common tool that we can deploy across different countries. We’re not there yet but it’s our ambition. I’m convinced it will help us to go further with the support we’re providing to patients.”

Another important avenue the group is pursuing is expanding into other areas of clinical oncology treatment outside of radiotherapy:

“Radiotherapy will remain our core area of expertise. But if one wants to provide the best care, and reach patients as early as possible, we need to increase our presence across the oncology pathway. We have done this in the past where it was needed in several countries: we have offered chemotherapy and have developed brachytherapy. But we want to do more of this now and do it in a more systematic way.”

“As a clinical oncology platform, it is important to take a holistic approach and pursue the most adapted pathways. Notably, the evolutions of theragnostics, immunotherapy, and nuclear medicine are happening very quickly. As a leading and fast-growing player in clinical oncology, we believe that healthcare providers need to steer their organisations towards solutions focused on the “four Ps”. Predictive, Preventive, Personalised, Participative care.”


Partnering with Public Healthcare to Strengthen Healthcare Systems

Most of Amethyst’s activity is for and with the public sector.

“We contract with public healthcare and public hospital facilities; this is our basic model. The public is facing an ageing population, with an increasing cancer prevalence, and the means available to public facilities are limited. We help public healthcare systems to face those evolutions. We come in with a different way of operating to the public sector,” Carré explains.

“Often, we work directly with public providers on a public-private partnership (PPP) basis. We have a few PPPs in Italy and Poland, and we just signed our first PPP in France. This is an important development because it allows us to help public facilities to invest where they otherwise might not be able to. We invest on their behalf, run the centres on their behalf, allowing them to provide the right treatment at the right place and keep the number of patients they need.”


Amethyst’s Four-Part Strategy for Future Growth

In terms of future expansion, Carré identifies four routes Amethyst is pursuing for growth:

“At the level of each country, we identify white zones where radiotherapy is lacking, and try to find a solution, either through network extension, or building greenfield centres. Secondly, we’re always trying to increase capacity in existing centres, by investing in new techniques.”

“The third way we can expand is by entering new countries. The preferred way to do this is by acquiring. Once we have acquired, we look at how to improve the capacity, by investing in new techniques.”

“And finally, we’re also on the lookout for the right opportunities to enter new markets by acquiring a large player. Of course, such opportunities are rare — in the six countries in which Amethyst is present, there is no equivalent in terms of footprint and capacity to reach and treat patients. But there are a few potential candidates across Europe.”


For further insights, read the full interview with Stéphane Carré on Healthcare Business International.

Clinical routine with Exac Trac Dynamic Surface

In the latest Brainlab Journal article, explore how the Radiotherapy Institute in Creil, Amethyst Radiothérapie France is revolutionising cancer treatment through SGRT, tattooless treatment and the breath hold workflow.

Now, with both ExacTrac Dynamic® and ExacTrac Dynamic Surface® for patient positioning and monitoring they are able to enhance daily clinical routines and ensure top-notch care for patients from all across the Sud l’Oise region of France.

Article below:


SGRT & Tattooless Treatment – How Radiotherapy Institute in Creil Is Improving Daily Clinical Routine with ExacTrac Dynamic Surface

We were excited to sit down with Andres Huertas, MD, radiation oncologist, and Pierre-Alexandre Rigaud, medical physicist, both from the Radiotherapy Institute for the Sud l’Oise region in Creil, France which is part of Amethyst Radiotherapy Group.

Dr. Huertas and Mr. Rigaud discuss with us the value of the latest radiotherapy techniques and technology in the treatment of cancers. The clinic, located within the medical campus of the public hospital Groupe Hospitalier Public du Sud de L’Oise Creil (GHPSO), is equipped with both ExacTrac Dynamic and ExacTrac Dynamic Surface systems for patient positioning and monitoring during radiation treatment for cancer. The clinic expanded in 2010 after becoming part of the Amethyst Radiotherapy Group and patients come from all over the region for advanced and comprehensive cancer care.


You have already been using ExacTrac Dynamic on your TrueBeam linac for over three years. What made you decide to equip your other linac with ExacTrac Dynamic Surface?

Dr. Huertas: “Our first ExacTrac Dynamic system has greatly benefitted our patients presenting with indications that benefit from stereotactic radiosurgery and body radiation therapy. The addition of ExacTrac Dynamic Surface, the new surface-only system by Brainlab, allows us to standardize the department: We are now able perform tattooless prepositioning for all our treatments. Furthermore, we are able to split clinical indications between the two machines depending on patient needs and the type of treatment to be performed.


Now that you have two ExacTrac systems, how do you plan to coordinate the daily clinical routine of the department between the technologies?

Dr. Huertas: “We will continue to perform cranial stereotactic radiosurgery (SRS) by leveraging the unique benefits that ExacTrac Dynamic brings to such treatments, like the X-Ray verification and active correction in six degrees of freedom, even at non-coplanar angles. With the breath hold workflow we have already treated over 200 breast patients and about 100 lung, adrenal gland and some liver cases. For such indications, the automated breath hold gating functionality is crucial as it ensures safe and accurate irradiation that avoids the heart and other critical organs. Our plan for the future is to perform primarily SRS and breath hold treatments on ExacTrac Dynamic and to focus more on thoracic, pelvic and other breath hold cases on ExacTrac Dynamic Surface.


What do you value most in the new ExacTrac Dynamic Surface Breath Hold Workflow?

Mr. Rigaud: “What we really like about the new workflow is that the software has been designed with the needs of clinicians in mind. For example, the simple feedback display for the patient in the bunker and on the control-room display, where they can easily see when they have reached the planned breath hold level, is a tool that provides reassurance to the patient that they are positively contributing to the success of the treatment. In turn, this gives us the confidence that we are performing a precise treatment. One of the major factors contributing to the accuracy is that the system automatically captures a reference surface for monitoring at breath hold level during external positioning imaging. This is a real game changer, providing the highest accuracy on the market for this treatment, as we can be sure that we are treating the tumor as planned. Last but not least, the preparation for the treatment is very simple and straightforward – no additional camera is needed in the CT room, we simply acquire two planning CTs, one at breath hold and the other in free breathing.


What are the benefits of tattooless workflows in your opinion and how exactly does ExacTrac Dynamic Surface help you achieve this? 

Dr. Huertas: “There is great value in surface-guided patient prepositioning and set-up for patients, as they are no longer marked with permanent and invasive tattoos that constantly remind them of their cancer treatment. Patients have found that tattooless treatments not only provide a cosmetic benefit but may reduce their anxiety, making the whole procedure more comfortable for them. For us, the advantage is that we can perform prepositioning that is comparable in accuracy and speed, and we don’t have to deal with the tattooing process, which can be very time consuming and tedious.”

Mr. Rigaud: “When we started transitioning from laser-based to tattooless prepositioning, we established that the precision of prepositioning with ExacTrac Dynamic Surface is as accurate as with lasers, but more straightforward and seamless. With the ExacTrac Dynamic Surface technology we can track patient surface anatomy directly, via a structured blue light projected onto the patient, which is acquired by two stereoscopic cameras. In this way we can very accurately track the surface without the need for any skin markings. We really appreciate the ease and speed of this setup process.”


What additional value do you see in relying solely on ExacTrac Dynamic and ExacTrac Dynamic Surface technologies in your department? 

Dr. Huertas: “Our staff, especially the radiation therapists (RTT), truly appreciate the ease of use of the Brainlab software and how the ExacTrac user interface allows them to make accurate but quick decisions as the treatment progresses. Because the software is the same on both systems, our RTTs were able to master the new ExacTrac Dynamic Surface system within days of installation. For example, they can use the ExacTrac Dynamic system one day and then switch to ExacTrac Dynamic Surface the next day without any problems. We feel that this standardization really helps us to streamline our clinical routine. In addition, patients can be easily moved between the two systems as they share one common patient database giving us further flexibility in our patient scheduling.”


What is your vision for the future development of the department in terms of hypofractionated treatments and SBRT? 

Dr. Huertas: “Nowadays, radiotherapy is going toward hypofractionation or extreme hypofractionation, to benefit more patients. This is backed up by more and more solid prospective data and will require an adaptation in our practice, from both medical and technical viewpoints. Delivering more dose per fraction comes with a higher risk for each fraction which can be mitigated by using advanced patient positioning and monitoring, which we feel confident in doing given the capabilities ExacTrac Dynamic offers combining SGRT and IGRT.

We have already started to use the system for lung and liver SBRT and plan to use it for prostate SBRT with the implanted marker workflow, given the features such as automated marker detection and active intrafraction motion management via stereoscopic X-Ray monitoring ExacTrac Dynamic offers. When we perfect our program for such treatments, we can always upgrade the ExacTrac Dynamic Surface to the complete system, which should be simple and quick, and therefore of great value for us.”

Amethyst Radiotherapy Secures €300m in Financing from Ares Management to Accelerate Growth Across Europe

Amsterdam, June 12th 2024 – In a significant stride towards enhancing access to advanced cancer treatment, Amethyst Radiotherapy Group has secured a landmark €300 million financing agreement with Credit funds managed by Ares Management Corporation (“Ares”), a leading global alternative investment manager.

This investment positions Amethyst as a leading player in the European oncology sector, as it continues to accelerate its expansion.

Facilities provided by Ares aim to fuel Amethyst’s ambitious growth plans, enabling investments in cutting-edge radiotherapy technologies and the establishment of new treatment centres across Europe. By broadening its footprint, Amethyst aims to bring innovative cancer care to more patients, addressing the escalating demand for accessible and high-quality oncological services.

This partnership with Ares marks a pivotal moment for Amethyst and the patients we serve,” said Stéphane Carré, CEO of Amethyst Radiotherapy. “With their support, we can intensify our efforts to deploy the latest treatment innovations and elevate the standard of cancer care throughout Europe.

Amethyst’s CFO, Andrew Nelson, echoed the sentiment, stating, “The facilities secured will support strategic acquisitions and capacity enhancement, positioning us firmly among the frontrunners to redefine the European cancer treatment landscape. We are delighted to be working with Ares, and we are confident that they will be an excellent partner for Amethyst in the years ahead.

Michael Dennis, Co-Head of European Credit at Ares Management, expressed confidence in Amethyst’s vision, noting, “We are thrilled to support Amethyst Radiotherapy in its vital mission to deliver high-quality, advanced cancer treatments across Europe. We have confidence in Amethyst’s strategic vision and long-term value creation potential, and we look forward to seeing the impactful advancements in healthcare outcomes that our partnership is expected to enable.

As major players in the private oncology sector vie for market share, Amethyst’s strategic financing deal with Ares solidifies its position as a formidable force, poised to drive transformative change in cancer care accessibility and quality throughout the region.

As featured in: investorsinhealthcare.com and FinSMEs

A new centre in Romania

A new Amethyst center opened in July 2021, at Timisoara (in the south-west of Romania) providing ambulatory treatment for all cancer types patients. This center is very similar to the Cluj center, with Radiotherapy Department equipped with BigBore Phillips CT, 2 mirrored ELEKTA LINACS providing VMAT/IMRT 6/10 MV with Agility fast MLC and a Medical Oncology Department functioning as Day Unit Hospital. Nutrition and psychological support will be provided in the center.

👉 Click here